June in Cayo Santa Maria is the cloudiest month of the year. In June, the weather in Cayo Santa Maria is typically hot. Average daily high temperature in June is about 29 degrees above zero. On average, Cayo Santa Maria has 11 rainy, 9 partly cloudy, 8 sunny, and 2 cloudy days in June. The rains are usually heavy. June as well as September and October is considered the most uncomfortable time to visit Cayo Santa Maria.