January in Knoxville is the coldest month of the year. In January, the weather in Knoxville is typically cold. Average daily high temperature in January is about 6 degrees above zero. On average, Knoxville has 11 partly cloudy, 9 rainy, 9 sunny, and 2 cloudy days in January. The rains are usually heavy. January as well as February, March, and December is considered the most uncomfortable time to visit Knoxville.