April in Mỹ Tho is the hottest month of the year. In April, the weather in Mỹ Tho is typically hot. Average daily high temperature in April is about 33 degrees above zero. On average, Mỹ Tho has 19 rainy, 7 cloudy, 3 sunny, and 1 partly cloudy day in April. The rains are usually heavy. April as well as May, June, July, and August is considered the most uncomfortable time to visit Mỹ Tho.