April in South Padre Island is the windiest month of the year. In April, the weather in South Padre Island is typically warm. Average daily high temperature in April is about 23 degrees above zero. On average, South Padre Island has 11 sunny, 11 partly cloudy, 5 rainy, and 3 cloudy days in April. The rains are usually moderate. April as well as March and May is considered the most comfortable time to visit South Padre Island.