June in Cayo Largo is the cloudiest month of the year. In June, the weather in Cayo Largo is typically hot. Average daily high temperature in June is about 28 degrees above zero. On average, Cayo Largo has 11 rainy, 9 partly cloudy, 8 sunny, and 2 cloudy days in June. The rains are usually heavy. June as well as August, September, and October is considered the most uncomfortable time to visit Cayo Largo.