December in Missoula is the most freezing month of the year. In December, the weather in Missoula is typically freezing. Average daily high temperature in December is about 1 degree below zero. On average, Missoula has 10 partly cloudy, 8 snowy, 8 cloudy, and 5 sunny days in December. The snowfalls are usually moderate. December as well as January, February, March, and April is considered the most uncomfortable time to visit Missoula.