In May, the weather in Santa Cruz del Quiché is typically warm. Average daily high temperature in May is about 23 degrees above zero. On average, Santa Cruz del Quiché has 21 rainy, 6 partly cloudy, and 4 sunny days in May. The rains are usually heavy. May as well as June, July, August, and September is considered the most uncomfortable time to visit Santa Cruz del Quiché.